Back Shot of a Bodybuilder Wearing Headphones and a Cap

Hypertrophy, or muscle growth, is not exactly rocket science. Understanding how it all works though, does require some basic knowledge. In this article, I will be discussing what hypertrophy is and how you can achieve it.

What is Hypertrophy?

It is general knowledge that resistance training leads to an increase of muscle strength. This is because of hypertrophy. It is an effect that we teach our central nervous systems.

  • Hypertrophy is an increase of the diameters of individual muscle fibers. It is most visible in type II muscles, which excel in explosiveness and raw strength.
  • Hyperplasia is an increase of the amount of muscle fibers. These fibers consist of myofibrils. Hyperplasia causes myofibrils to increase in number.



The latest scientific studies have proven that muscle growth for the most part has to do with hypertrophy. However, the effects of hyperplasia should not be thrown away just yet.

Research has shown that muscle growth through hyperplasia exists within animals. It could also contribute to human muscle growth. Furthermore, hyperplasia increases the amount and strength of connective tissues.


Hypertrophy on a Cellular Level

During contraction, the belly of the muscle expands. This causes connective tissues to become longer, which then stabilizes muscular tissue.

Thick muscle fibers contain a lot more contraction proteins than thin muscle fibers. This influences the rate of contraction. A muscle that has gained in mass contains more connective tissue, which makes the muscle more compact, more powerful and more resistant to injuries.

This is what actually happens if you exercise.

The type of muscle fibers has an important effect on whether a muscle can contract fast and powerful, or slower and less powerful. Different muscle stimuli will result in different muscle activation.

Click here to learn more about the difference in muscle stimuli.


So How Do You Develop Muscle Growth?

I’m sure some of you might be asking yourself what the use of all the previous information is. We’re getting there, don’t worry!

Muscle growth is encouraged by stimulating them in different ways. So how should you train? Well, that all depends on your personal goals and aspirations.

Click here to learn more about making your own workout plan.



In general, loading your muscles with 60-75% of your 1RM (the maximum weight you can handle for 1 rep) for a duration of 8 to 12 reps. However, it is entirely possible to gain more muscle mass with fewer reps.

Lifting up to 75% of your 1RM is recommended to beginners, though. Why? Well, because beginners often have no idea how to handle heavy weights. Therefore, one of the first things you should do when you’re starting in the gym, is determining your 1RM.

So, do you just go ahead and try to pick up a tremendously heavy weight? Well, that’s one way to determine your 1RM, but I would not recommend it because of the risk of injury.

Let’s say that you’re performing a set of 80 lbs squats, consisting of 10 reps. You can then make it easy for yourself if you take a look at the pyramid above. This 80 lbs is 75% of your 1RM, therefore your 1RM equals about 107 lbs.

Most hypertrophy workouts are carried out at 60-75% of the 1RM, often in 3-5 sets of 8-12 reps. It is important to lower the weight slowly (1-2 seconds) during what is called the eccentric phase. The concentric phase, should be explosive and short. To clarify: the weight should be moved with a lot of force.

Always keep a good form in mind. If you can’t carry out an exercise while using proper form, you will have to lower the weight.

Good exercises that promote hypertrophy include heavy compound exercises, as well as isolation exercises. The combination of both allows for muscles to be stimulated in multiple ways.

And what about rest?

Indeed, let us not forget about recovery. Most research states that about 48-72 hours is needed for muscles to fully recover. It can differ from person to person, though. Some people recover faster.

Muscle recovery is just one part of the recovering process, though. Strength training can really tax your central nervous system, which sometimes requires up to 96 hours (4 days) to fully recover. You don’t want to go too far with your workouts.

It’s important to listen to your body. If it has been 48 hours since your last workout and you’re barely able to move because your muscles are sore, just take the day off or do some light exercises.


Hypertrophy Post Injury

Training for hypertrophy isn’t something you can blindly start. If you want to start working out after an injury, it is recommended that you don’t immediately start trying to build muscle mass.

Recovering from injury requires three elements to be trained.

  • Strength
  • Speed
  • Endurance

Hypertrophy training is classified as strength training. However, the first thing you should be training when you’re fresh from injury, is stability. You can then slowly start training endurance, speed and strength.

Keep in mind that these exercises should be done with about 50-60% of your 1RM, for the duration of 15-20 reps per set. This way, you won’t tax your muscles too much, but you’re still able to train the movements that are required to train with heavier weights later on.

Remember to always perform these workouts together with a physiotherapist.



In Conclusion

Hypertrophy in a nutshell is the strengthening of connective tissues and muscle fibers. This causes muscles to become more compact, harder and stronger.

The most common way to accomplish muscle hypertrophy, is to do workouts with weights between 60 and 80% of your 1RM. You can calculate your 1RM with the first pyramid in this article.

Furthermore, studies have also shown that a lower amount of reps with more weight can lead to more hypertrophy. Lifting heavy increases strength and therefore muscle mass. I will be exploring this topic in a future post.

Please, leave your thoughts or questions in the comment section below!


Frequently Asked Questions

What is hypertrophy?

Hypertrophy is an increase in type II muscle fiber size, and therefore muscles in general.

How do you promote hypertrophy?

Generally speaking, loading your muscles with 60-75% of your 1RM for 3-5 sets, with a duration of 8-12 reps is very effective to promote muscle growth.

What exercises are best for hypertrophy?

A combination of heavy compound exercises and isolation exercises has proven to be the best way to stimulate muscle growth.

12 thoughts on “Everything About Hypertrophy

  1. Iets say this is a power packed article with lot of good information about hypertrophy that would help us understand it better.knew alot about hyperplasia but a little about hypertrophy but now I know it has a lot of positive effect on the human body I would give my self more to HIT

    1. Hi Feji,

      Thanks! I’m glad you like my content. High Intensity training does indeed promote hypertrophy a ton! 


  2. This is an awesome article that I am going to send my godson. He is in intensive training and I feel that he doesn’t know enough about his body muscles. He has recently injured himself and has absolutely no idea what to do to make himself better.  This is going to help him out a lot. Very informative. Thank you.

    1. Hi there,

      Thanks for dropping by and sharing my content! I definitely hope your godson finds is useful, too. Not being sure how to train after injury can really slow down your recovery.

      Have a great day! 

  3. I love all your knowledge in these areas of fitness. It’s good to know the differences between Hypertrophy and Hyperplasia. You have a wonderful setup of info. but would be interesting to see some Humor inserted … ie.. cartoon characters demonstrating the examples you describe. Just a thought…. 

    Good luck to you in your future 

    1. Hi Jessie, 

      Thanks for leaving your thoughts! I will admit, this article might not be the most interesting one to some, and therefore I’m trying to write it in a way that appeals to most. I currently make a lot of pictures that I make myself, but you gave me some ideas, so thanks for that! 

      Have a great day! 

  4. Being medically trained, I have always thought of hypertrophy to be a bad thing… hypertrophy of the heart muscles leads to an organ that no longer functions in the right way. But I had not thought about it in a positive way. A very interesting article. My son is going through rehab right now for a stomach strain and we have moved into core strengthening after a period of a few weeks of physiotherapy.

    1. Hi Helen,

      Hypertrophy of the heart can indeed have negative effects. Hypertrophy of skeletal muscle tissue though, can have very positive effects. 

      Best wishes to your son! 

  5. Hello Kevin. Thank you for sharing these insights on the basis of hypertrophy. I have never heard the terms hypertrophy and hyperplasia before now. I have gotten a well detailed information about those two terms from this post. I have discovered so far that lifting heavy weight is beneficial to develop our strength, muscle etc, it improves hypertrophy. Thanks for sharing some tips here.

    All the best!

    1. Hi there,

      Thanks for dropping by. I’m glad you learned a thing or two. Heavy weight, i.e. high Intensity, indeed promotes muscle growth as your body tries to adapt to lifting heavy.


  6. Hey Kevin, Your guide is awesome on all thing you write. Your article give me motivation to do workout etc. I am visiting your site 3rd time today. I am in learning stage and you provide all information needed to develop and better time routine etc. From your data I found this very important.

    Hypertrophy in a nutshell is the strengthening of connective tissues and muscle fibers. This causes muscles to become more compact, harder and stronger.

    Thank you Parveen

    1. Hi Parveen,

      I’m glad you like my content and I hope it will help you to reach your personal goals!

      Have a great day.

Leave a Reply

Your email address will not be published. Required fields are marked *